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Literature Highlights Issue 2

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PROTACs and molecular glues

Concept to Clinic

New Therapeutic Modalities

Interaction Analysis

Poster
Poster
Design, Preparation, and Screening of BRPF1b Degraders

Cell Based Assays

Assay Card
Assay Card
Investigating Tumour Cell Killing Through 2D and 3D Assays

Oncology

Assay Card
Assay Card
Advancing Drug Discovery with 3D Spheroid Cancer Models

Concept to Clinic

Artificial Intelligence

Brochure
Brochure
BioPALS Brochure

Medicinal Chemistry

In vitro ADME & DMPK

Flyer
Flyer
MedChem Concepts – hERG

Immuno-oncology

Cell Based Assays

Poster
Poster
Priming of spheroids with IFN-γ increases efficacy of T cell mediated killing with PD-1 blockade

Synthetic Chemistry

Publication
Publication
Literature Highlights Issue 1 April 2024: N-Containing Heterocycles

Biophysical Characterisation

Cell Based Assays

Molecular Biology

Spatial Biology

Structural biology

Brochure
Brochure
In-CERT Brochure

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Poster
Poster
Implications of Targeting Novel Pathways in Exhausted T Cells for Immuno-Oncology Therapeutic Intervention

Virtual Screening

Computer Aided Drug Discovery

Biophysics

Hit Generation

Poster
Poster
Introducing BioPALS – A Versatile Hit Identification Technology Powered by AI and Enabled by GCI

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