Spatial Biology Services

Map disease and therapeutic response within tissues at the single-cell level

Spatial biology services provide the insight you need to understand how your therapeutic interacts with complex tissue environments. Whether you’re selecting patient samples for suitability, evaluating biomarker expression, or tracking therapeutic response in vivo, our specialist team can accelerate your work from early discovery through to clinical trials.

Explore how our CRO services for spatial biology can provide you with leading expertise and a flexible approach that seamlessly integrates with your drug discovery and development processes.

Discuss your project with our spatial biology scientists

Successful spatial biology studies require specialist expertise and capabilities. Our experienced team guides you in selecting the most appropriate approach to achieve your objectives and is supported by state-of-the-art technology for rigorous execution and rapid turnaround. Since 2014, we’ve supported numerous clients with spatial biology services, with over 75% of clients returning to us for their next project.

By combining expert assay design, cutting-edge technologies, and a collaborative approach, we help you:

Understand tissue composition and biomarker localization in healthy and diseased samples
Assess therapeutic response in context—at cellular and spatial resolution
Validate targets and develop biomarker strategies with spatial relevance
De-risk candidate progression with robust in situ data from preclinical and clinical samples

Spatial biology capabilities to support your research goals

Histological staining and pathology assessment using routine stains such as H&E and specialized stains like Verhoeff Van Gieson
Automated staining to ensure consistency and traceability
Single-marker or multiplex detection of RNA and proteins in situ at the single-cell level
Pre-optimized and customized multiplex panels for 2–100+ markers, including RNA–protein co-detection
Spatial transcriptomics and proteomics for in-depth molecular profiling
Image analysis workflows using Visiopharm® imaging software for quantitative interpretation of whole-slide images

Designed to support complex projects

GCP-compliant workflows: Suitable for clinical trial support and regulatory submissions
Akoya Qualified Service Provider: Recognized for excellence in multiplex spatial biology
End-to-end support: From tissue acquisition to image analysis
Flexible assay design: Customized panels and protocols to meet your unique needs
Quantitative analysis: Powered by Visiopharm®, delivering precision and reproducibility

A flexible, collaborative approach ensures success on your terms

We tailor your project design to your needs

Every project is different. We collaborate with you to build a study that addresses your scientific questions and sample constraints, using the most appropriate spatial biology tools.

A project team dedicated to you

You’ll work with the same expert team throughout your project—ensuring continuity, context, and clear communication. Our experienced project managers and scientists act as an extension of your in-house team.

Biomarker knowledge from discovery to clinic

Whether you're validating a novel biomarker, developing a companion diagnostic, or screening clinical samples, we bring expertise in biomarker assay development at all stages of the drug discovery pipeline.

We care about your samples

From tissue prep to analysis, your samples are handled with care. We customize protocols to your tissue type and endpoint needs, applying our expertise across histology, immunohistochemistry, and digital pathology to maximize quality and insight.