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Understanding Thyroxin Modulation

In vitro assays for your chemical or agrochemical regulatory submission

Do you need to understand thyroxin modulation mechanisms for the regulatory submission (CLP guidance, EFSA, ECHA) of your chemical or agrochemical?

We can help you investigate comparative UGT/UDPGT induction and identify species-specific differences in thyroxin (T4) modulation mechanisms.

As part of our thyroxin modulation assessment platform, this in vitro UGT/UDPGT induction assay allows you to address questions about human relevance and navigate regulatory concerns. It is used to fulfil data requests for safety profiles and human health risk assessments.

Why our approach stands out

  • Robust: Reliable and consistent results
  • Validated and available to GLP: Supported by historical data
  • Regulatory Ready: Designed for submissions to regulatory bodies

Want to know more? Download our poster today.

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